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2.2.2 Errors in Gonadal Differentiation and Development

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2.2.2 Errors in Gonadal Differentiation and Development

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Title: 2.2.2 Errors in Gonadal Differentiation and Development
Author: Marsh, Karen; Bruce, Brendan; La Barbera, Andrew R.
Description: GOAL: To describe the control of sexual differentiation and describe the consequences of defective regulatory mechanisms. 2.2 Objective: To describe the causes and manifestations of errors in differentiation and development of the gonads. 2.2.2 Error in Gonadal Differentiation and Development (Photo Gallery)

True Hermaphroditism
-What type of gonadal tissue do true hermaphrodites possess?
-What type of internal reproductive tract is characteristic of true hermaphrodites?
-What is the appearance of the external genitalia of true hermaphrodites?

Ovarian Dysgenesis
-What is the name of the most common form of ovarian dysgenesis?
-Describe the ovaries of patients with this disorder.
-What is the most common karyotype in this disorder?
-What are eight common characteristic of patients with this disorder?
-Would patients with this disorder have normal ovarian function?
-Would plasma level of reproductive hormones be high, low or normal?

Seminiferous Tubule Dysgenesis
-What is the name of the most common form of seminiferous tubule dysgenesis?
-What are the minimal numbers of X and Y chromosomes that define this disorder?
-What is the frequency of this disorder?
-What are the gonadal manifestations of this disorder?
-What are the four principal characteristics of this disorder which lead one to suspect this order in prepubertal boys?

Bookmark: http://hdl.handle.net/2374.UC/161
Date: 2008-08-15

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