2.2.2 Errors in Gonadal Differentiation and Development

Author
Marsh, Karen
Bruce, Brendan
La Barbera, Andrew R.
Issue Date
2008-08-15
Item Type
Animation
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GOAL: To describe the control of sexual differentiation and describe the consequences of defective regulatory mechanisms.
2.2 Objective: To describe the causes and manifestations of errors in differentiation and development of the gonads.
2.2.2 Error in Gonadal Differentiation and Development (Photo Gallery) <p>True Hermaphroditism <br/> -What type of gonadal tissue do true hermaphrodites possess? <br/> -What type of internal reproductive tract is characteristic of true hermaphrodites? <br/> -What is the appearance of the external genitalia of true hermaphrodites?</p> <p>Ovarian Dysgenesis <br/> -What is the name of the most common form of ovarian dysgenesis? <br/> -Describe the ovaries of patients with this disorder. <br/> -What is the most common karyotype in this disorder? <br/> -What are eight common characteristic of patients with this disorder? <br/> -Would patients with this disorder have normal ovarian function? <br/> -Would plasma level of reproductive hormones be high, low or normal? </p> <p>Seminiferous Tubule Dysgenesis <br/> -What is the name of the most common form of seminiferous tubule dysgenesis? <br/> -What are the minimal numbers of X and Y chromosomes that define this disorder? <br/> -What is the frequency of this disorder? <br/> -What are the gonadal manifestations of this disorder? <br/> -What are the four principal characteristics of this disorder which lead one to suspect this order in prepubertal boys?</p>
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